HNRNPA2B1 FACILITATES OVARIAN CARCINOMA METASTASIS BY SORTING CARGOES INTO SMALL EXTRACELLULAR VESICLES DRIVING MYOFIBROBLASTS ACTIVATION

hnRNPA2B1 facilitates ovarian carcinoma metastasis by sorting cargoes into small extracellular vesicles driving myofibroblasts activation

Abstract Background Ovarian carcinoma (OvCa) metastasis is initiated and boosted by tumor-stroma interactions mediated by small extracellular vesicles (sEVs) containing microRNAs (miRNAs).However, the mechanisms of sorting relevant miRNAs into tumoral sEVs remain elusive.Results In this study, among the RNA-binding proteins, hnRNPA2B1 was identifie

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Comparing HIV prevalence estimates from prevention of mother-to-child HIV transmission programme and the antenatal HIV surveillance in Addis Ababa

Abstract Background In the absence of reliable data, antenatal HIV surveillance has been used to monitor the HIV epidemic since the late 1980s.Currently, routine data from Prevention of Mother-to-child HIV transmission (PMTCT) programmes are increasingly available.Evaluating whether the PMTCT programme reports provide comparable HIV prevalence esti

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Going virtual during the COVID-19 pandemic: adaptation of a mixed-methods dietary behavior study within a community-based participatory research study of African-American adults at risk for cardiovascular disease

Abstract Background Identifying mechanisms to maintain CBPR studies during an infectious disease pandemic is vital.The current paper describes the changes in methods and processes conducted within a CBPR mixed-methods study to a virtual setting during the novel coronavirus (COVID-19) pandemic.Method The DC Community Organizing for Optimal Culinary

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